NCIS: Los Angeles' will go rouge in the season 7 premiere.

'NCIS: LA' Season 7: Will Kensi Meet Deeks' Mom? Daniela Ruah Previews Deeks' Hesitation

Callen (Chris O'Donnell) will go head-to-head with his own team in "Active Measures," and the agent's lone wolf act will leave him without any backup if his case goes south. Hetty (Linda Hunt) will quickly pull the plug on Callen's unsanctioned mission, leaving Sam (LL Cool J), Deeks (Eric Christian Olsen), and Kensi (Daniela Ruah) to bring him back in at "any cost."

"The seventh season premieres with Callen embarking on a secret project, leaving Sam and the entire team in the dark," CBS teased. "After Hetty demands his operation be shut down, the team is tasked with locating Callen before he finds himself in over his head."

'NCIS: LA' Season 7: Callen Must Be Stopped At 'Any Cost', Rouge Mission Jeopardizes Friendships

When Callen does reunite with Sam, it will be over a dead body. Viewers will have to wait and see if G's the one who laid the victim out or if the corpse is courtesy of whichever baddie Callen is after.

Click through the slide show to see what the premiere hold for Callen, Kensi, Deeks, Sam, Hetty, and Granger (Miguel Ferrer).

Find out more when NCIS: LA returns to CBS on Sept. 21 at 10 p.m. ET. Click the video below to see a preview for the series' season 6 finale.