'Supernatural' Season 12: What Will Put Sam & Dean At Odds? EP Teases 'Different Reactions' [VIDEO]

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If Supernatural's Winchester brothers can agree on one thing, it's the first half of their family's credo. 'Saving people' is always the goal, but, in season 12, Sam and Dean may find themselves at odds over the best way to do their job.

Sam (Jared Padalecki) and Dean (Jensen Ackles) closed out "Alpha and Omega" on the same page. For once, lying and subterfuge wasn't part of their best intentions, and season 12 will pickup where the finale left off. Once the British Men of Letters get involved, however, they'll be an opportunity for the Winchesters' legacy and hunter sides to cause a little friction.

"Initially, Sam is in trouble and Dean is extremely driven to save his brother. As this thing becomes more personal, and we come to understand the British Men of Letters and their point of view, our guys will have different reactions," co-showrunner Andrew Dabb told SFX Magazine. "I believe when the cards are down, Sam and Dean are on the same page all the time, which is to do the right thing. But what is the right thing for either one of them is not always agreed upon."

We're ready to bet Sammy will move to side with the MOL, even despite the fact that Lady Toni Bevell (Elizabeth Blackmore) will put him through the ringer in the premiere (see video below). The younger hunter is never more at home than when he's surrounded by a mound of research, just as Dean is never complete without a blade in his hand.

Meanwhile, the boys will also have different takes on the Mary (Samantha Smith) situation. While both brothers are over the moon to see their mother alive and well once more, but the question of the future will weigh heavy on the newly reunited family.

"We don't want to drive an unnecessary wedge between Sam and Dean, and I don't believe Mary will do that, but there will be a difference of opinion and there will be things raised that not everybody is on board with," Dabb teased. "The show revolves around Sam and Dean, and how they react to her is really the core of the seasons."

Find out more when Supernatural returns to The CW on Oct. 13 at 9 p.m. ET.

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