CBS's The Big Bang Theory is slated to honor cast member Carol Ann Susi in the wake of her death in November.

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Susi played Howard's (Simon Helberg) mother Mrs. Wolowitz on The Big Bang Theory for several seasons before her tragic death from cancer. The actress was 62. Now, the popular sitcom is giving her a tribute in an upcoming episode of the series.

In the episode The Comic Book Store Regeneration, Howard is hit with some shocking news in regard to his mom, which is presumably life changing, according to a new report by TVLine. Howard also discovers that the comic book store owned by Stuart (Kevin Sussman) is filled with his mom's old furniture.

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This will likely be a sad episode of The Big Bang Theory, assuming Mrs. Wolowitz dies. It will likely be a standout episode for Helberg.

As TVLine notes, this episode won't be entirely tragic as it will feature a cameo from Nathan Fillion. He will be appearing as himself at a restaurant where Raj (Kunal Nayyar) and Leonard (Johnny Galecki) are eating. The friends worry over whether or not this is indeed Fillion and decide to approach him for a picture.

Fillion is obviously a nerd icon having starred in such geek classics as Firefly, Buffy the Vampire Slayer and Dr. Horrible's Sing-Along Blog.

This episode is slated to air on Thursday, Feb. 19 in the regular 8 p.m. timeslot.

The Big Bang Theory airs Thursdays at 8 p.m. ET/PT on CBS.