Lisa Vanderpump is furious with her ex-bestie Brandi Glanville after she slapped her across the face and accused her of sleeping around with different men.

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During Tuesday night's new episode of Real Housewives of Beverly Hills, Glanville crossed the line and hit Vanderpump in the face, but that isn't the only mistake she made.

Apparently Glanville also accused Vanderpump of sleeping around with different men in Los Angeles and cheating on her husband Ken Todd.

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While out to dinner in Amsterdam, Glanville pointed at Vanderpump and jokingly said that if she needed help for sleeping around with half of L.A., she could always ask for help.

The clip has sparked a series of rumors and now Vanderpump is even more disgusted with Glanville.

The reality star took to Twitter to make light of the situation and to poke fun at Glanville for being 'crazy.'

Glanville recently opened up and the statement she made during their trip and she says it was just a joke.

"I have never ever said that, never thought it, and you know it's complete and total BS," the reality star wrote in her cast blog. "I was just continuing a long running joke that you started with me years ago. Ridiculous."

While Glanville is claming that she was simply joking with her ex-gal pal, Vanderpump has made it clear that she and her former friend will never have a friendship again because the ship has sailed. 

Real Housewives of Beverly Hills airs every Tuesday night at 9 p.m. on Bravo. Viewers can watch a sneak peek from next week's new episode in the video below.