Serena Williams is playing a match against Andrea Hlavackova from Czech Republic today for a post in the quarterfinals at the U.S. Open.

The match is Live Streaming on USOpen.org starting at 1:25 p.m. EST and broadcasting on CBS New York.

Williams won her first U.S. Open in 1997 when she was 17 years-old, now she is 30 years-old and she wants to prove that she can still win.

Williams has been through tough times in recent years and has had to overcome a series of health issues that derailed her career.

Williams will play for a second time Monday with her sister Venus in a doubles match with the fourth seeded team of Russia's Maria Kirilenko and Nadia Petrova at 7 p.m.

Other women's singles scheduled for today are No. 6 Angelique Kerber vs. No. 10 Sara Errani at 2 p.m, and No. 2 Agnieszka Radwanska against No. 20 Roberta Vinci at 4 p.m.

But perhaps one of the most anticipated matches today is No. 1 Roger Federer vs 23rd seed and veteran Mardy Fish at 3 p.m.

Also No. 3 Andy Murray from U.K. will face No. 15 Canadian Milos Raonic at 9 p.m.