It's time to get back to basics for Supernatural's Sam and Dean...

...or is it?

'Supernatural' Season 11: It's (Finally) Time To Talk About Adam, Jensen Ackles Drops Major Teaser

The Winchester brother's will take on an apparent haunting in episode 5, but a series of Lizzie Borden-related murders will take a dark(ness) turn during "Thin Lizzie."

"Sam (Jared Padalecki) and Dean (Jensen Ackles) investigate a series of murders at a local B&B that also happens to be Lizzie Borden's old home," The CW announced on Thursday. "When a local man, Len (guest star Jared Gertner), tells them he saw a little girl around the B&B around the time of the murders, the brothers realize Amara (guest star Yasmeene Ball) may be responsible."

'Supernatural' Season 11: Sam To Make A New 'Friend', Jared Padalecki Tease Upcoming Relationship

Should the boys reach for the salt, or something a little stronger? This monster-of-the-week case may have a little more bite than Team Free Will is prepared to handle.

Amara will continue to dominate the scene as Supernatural heads into episode 3, "Bad Seed." No longer a baby, the soul-eating child is now with Crowley (Mark Sheppard), and the Winchesters will need to track down the devilish duo while attempting to heal Castiel (Misha Collins).

Find out more when Supernatural airs Wednesdays at 9 p.m. ET on The CW.