Supernatural's Winchester brothers are ready to do everything - and anything - to take down the Mark of Cain.

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The Supernatural finale is upon us once more, and fans will be on edge from the opening bars of Carry On My Wayward Son to the final seconds of season 10. Sam (Jared Padalecki) and Dean (Jensen Ackles) are hell bent on sending the Mark packing, but the pair will take drastically different approaches to Cain's pesky brand during "My Brother's Keeper," making for another of the series' intensely emotional episodes.

"Both brother's will, no question, go to the end of the line, as it were, to get what they want this episode," executive producer Jeremy Carver recently teased (see video below). "Sam wants very much to save Dean while Dean wants very much to save the world form himself...Each brother is willing to take some very drastic measures. It's a very emotional, very dramatic episode [that] I think will be a satisfying conclusion to the season."

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With Cas (Misha Collins) ready to team up with Crowley (Mark Sheppard) and Dean calling in Death (Julian Richings) for a deal, "Brother's Keeper" is bound to be full of twists and turns, some of which will lead to "emotional whiplash."

"Well we're inching up on the finale here and this is, in typical Supernatural fashion, fans are going to experience emotional whiplash of 'Oh thank God' to "Oh sh-t!' in the last two beats of the season," Collins teased, according to Entertainment Tonight. "So there's some good and there's some terrible coming down the pipe."

Find out how the story plays out when Supernatural airs "My Brother's Keeper" on Wednesday at 9 p.m. ET.