Captain Marvel loses one of its main characters even before it starts filming as DeWanda Wise leaves due to scheduling conflicts.

Wise, 33, stars in the Netflix series She's Gotta Have It, which was renewed for its second season. Although filming for the show has not commenced, the actress cited conflict of schedule as the reason to drop her Captain Marvel role as Nola Darling.

Expanding Marvel Universe

The Marvel universe is expanding year-on-year as comic characters are relived in the big screen. Captain Marvel is based on the 1968 comics about Carol Danvers played by Brie Larson.

Her superhuman abilities started when her DNA was accidentally infused with that of an alien during an accident. The result gave her massive strength, energy projection, and flight capability.

The movie casts Samuel L. Jackson, Jude Law, Ben Mendelsohn, and Gemma Chan. Rumor has it that the plot is set on the '90s with Skrulls as the primary villain. The screenplay is still under works, so there is no finality on the fate of the characters.

Larson will not appear in the upcoming Avengers: Infinity War to be shown on April 27. However, she is tapped to play in the movie's sequel, Avengers 4, which will be released two months after Captain Marvel in 2019.

Filming for Captain Marvel will start late March, although the production is yet to announce a replacement for Wise. Critics speculated that since Wise's departure from the movie was formally tendered a few weeks ago, it is possible that the producers have already gone through another set of casting calls.

Other Marvel movies pending release are Ant-Man and the Wasp on July 6 and the sequel to Spider-Man: Homecoming on July 5, 2019.

Battling Depression

Despite her current success in film and television, Wise is also vulnerable to negative emotions. During the celebration of International Women's Day, the actress revealed in social media that she has been suffering from sadness and depression.

"Ya girl got some pretty challenging news this week, & on this #InternationalWomensDay I find myself battling sadness and #depression. Still, I'm thankful for the highs and lows. Combined, they make me both confident and compassionate. In them, I find just how strong my weaknesses are," Wise said.

Wise did not mention the cause of her depression, yet fans expressed their support on Instagram.

"Thank you to all the women whose resolve & tenacity keeps me going. If you're battling something today, let's make another day together," added Wise.