The Sinister Six super villain team-up is something not seen before in Hollywood so how the story would go is still in question. But could it revolve around the villains teaming up for individual fight with Spider-Man?

Director Talks 'Sinister Six,' Possible Cameos & What Could Happen During The Movie

As of right now, there is no word if Andrew Garfield would show up as the famed webslinger in the movie, but without him, it begs to question who the villains can fight outside of internal conflicts.

In the original comics, after suffering three defeats in a row from Spider-Man, Doctor Octopus contacts every known supervillain that had crossed paths with Spider-Man. Only Vulture, Electro, Kraven the Hunter, Mysterio and Sandman respond. As none of the members are willing to relinquish the honor of killing Spider-Man themselves, they decide to challenge Spider-Man individually, with the order in which they face him determined by random drawing.

'Chronicle' Star Dishes On 'Sinister Six' & Being In A Franchise

The Sinister Six kidnap Daily Bugle secretary Betty Brant and Aunt May, holding them hostage in order to force Spider-Man to confront them. Spider-Man defeats the Sinister Six one-by-one, mocking their decision to battle him individually instead of as a team.

This is an interesting route for the movie to take as it would allow for the villains to team-up and interact before each having an individual fight with the hero. But it also puts a lot of responsibility on Spider-Man to show up.

The thing that does work about that is it would allow the franchise to have Garfield show up and participate in fights without having to put in much time outside of the fights. Spider-Man wouldn't be the main focus and he wouldn't have to drive the plot of the story, which could be a change of pace for Garfield, and maybe entice him to come back because the workload is smaller.

Sinister Six is set to open in theaters on November 11, 2016.