It's time for science vs. legend to go head to head on The X-Files, and we all know which side Mulder will land on.

'The X-Files' 2016: More William News On The Way? Chris Carter Teases 'Home Again'

Mulder (David Duchovny), Scully (Gillian Anderson), and two new FBI agents will need to find a way to communicate with an unresponsive bomber in "Babylon," and while the Doc will turn to the world of medicine, the believer will look for a less traditional answer.

"When an art gallery that's showing potentially offensive artwork is bombed, Mulder and Scully seek some way to communicate with the comatose bomber in order to prevent a future attack," Fox teased. "Meanwhile, a pair of younger FBI agents on the case (guest stars Robbie Amell and Lauren Ambrose) push Mulder and Scully to examine their own beliefs as Scully seeks answers from neuroscience and Mulder from mysticism."

'The X-Files' 2016: More Episodes In The Works? David Duchovny Teases Post-Revival Plans

Expect Mulder's line of inquiry to send him for a psychotropic loop. If you miss The LoneMan, episode 5 is a can't miss.

"[The Lone GunMan are] back in an unexpected way in episode 5 where you also see a new side of Mulder that you've never seen - involving a psychotropic drug," series creator Chris Carter told Entertainment Weekly.

Find out more when The X-Files airs Mondays at 8 p.m. ET on Fox. Click the video below to see a promo for the series' next episode, "Mulder and Scully Meet The Were-Monster."