Angelina Jolie is receiving high regards from both Hollywood and the general public for her candid New York Times op-ed about her double mastectomy and other steps she has taken to prevent an occurrence of cancer, which killed the actress' beloved mother. Now Jolie says she is taking yet another bold step for her health.

Jolie tells PEOPLE exclusively in their new issue, hitting newsstands Friday, that she will also undergo surgery to remove her ovaries. Jolie admitted in her Times story that she has the "faulty" BRCA1 gene, which puts her at an especially high risk of breast and ovarian cancer. Jolie's doctors have estimated that she has a 50% chance of developing ovarian cancer.

Doctors recommend that women have the procedure, known as an oophorectomy, by age 40 or when they have decided they are done having children, though it is likely to trigger an early menopause. Premenoupausal women with BRCA gene mutations who have had the surgery reduce their risk of ovarian cancer by 85% to 95%, according to the American Cancer Society.

In addition, The Daily Mail reports that her impending wedding to long-time partner Brad Pitt will be moved up due to her health concerns. The couple has been engaged since 2011. "Angie is keen on a wedding and the kids are clamoring for a marriage and keep asking Brad and Angie when it's happening," according to a MailOnline source.

Pitt claimed in November that they would be marrying "soon."

"I am getting more pressure from my kids, and it is something I want to do within their lifetime," he admitted at a screening of his recent film Killing Them Softly. "I also feel like the time has come. The time is nigh. It's soon. I got a good feeling about it."

Jolie has been leaning on Pitt and their family as a support system during her health crisis. They are said to have maintained common family traditions, such as their Valentine's gift exchange and Easter egg hunt, during the three-month period when Jolie had her breast surgery. "Her kids always come first to her," a Jolie-Pitt family insider told the magazine.

Dr. Mehmet Oz, cardiac surgeon and television host, described the Jolie announcement yesterday to PEOPLE as "a kick in the pants."

"It changes everything on how we perceive cancer prevention," Oz said. "This shows us what the future of cancer will look like.

"What Angelina did was to change the dynamic - when a young, sexy woman electively, because of remarkable advancements in technology, allows some of her most sensuous parts to be removed in order to save her life so she can be here for her kids, that's a seismic shift." 

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