When it comes to the world of South Park, nothing is off limits.

Chatter On 'South Park' Washington Redskins Controversy

The controversial and highly acclaimed animated series returns to Comedy Central for its 19th season where it will tackle real-life scandals- this includes the New England Patriots deflategate incident as well as Caitlyn Jenner's transition.

In fact, a clip was released that shows Cartman talking to his fellow students about detention. In his usual angry tone, he says he's going to "Tom Brady this thing" by demanding he'll do one day of detention instead of four. This is likely a satire on Brady's suspension from the NFL due to the deflategate scandal.

'South Park' Lawsuit Copyright Infringement Chatter

Cartman changes his mind in the clip and says he's getting zero detention days...and then it gets more enticing.

"I'm gonna go home! And f--k my hot wife!" the character exclaims. "Who's not even that hot, kind of looks like a dude!"

Is this a take on Caitlyn Jenner becoming a woman after she was formerly known as Bruce? Whatever the case may be, TV Line did make it clear that the new season will have a tackle on the popular reality star.

Fans can expect a lot more craziness going on based on the synopsis for the new season.

"There is a new principal at the helm of South Park Elementary," the plot reads. "He forces the boys to confront the damage they've done through their history of racism and unconscious basis. It is the most stunning and brave South Park ever."

South Park Season 19 premieres on Wednesday, September 16 at 10 p.m. ET on Comedy Central.

See the sneak peek below.