'McDreamy' is officially single and back on the market.

Patrick Dempsey, who portrays Dr. Derek Shepherd  (also known as Dr. McDreamy) on the hit ABC drama Grey's Anatomy, and his wife of 15 years, Jillian Fink, are currently in the process of a divorce.

According to Us Weekly, Fink was the first to file for divorce from the Grey's Anatomy star, citing irreconcilable differences, and is seeking joint custody of the couple's children, Tallulah Fyfe, 12, and 7-year-old twins Sullivan Patrick and Darby Galen. She is also reportedly seeking spousal and child support.

"It is with careful consideration and mutual respect that we have decided to end our marriage," the couple said in a joint statement. "Our primary concern remains the well-being of our children, and we ask with profound gratitude that you respect our family's privacy at this very sensitive time."

The two wed in 1999, and reportedly do not have a prenup. Dempsey is estimated to be worth $40 million.

This was Dempsey's second marriage, as he was previously married to Rocky Parker from 1987 to 1994.

Fink has been a makeup artist and hairstylist on movie sets. Dempsey is best known for his work on Grey's, in addition to his roles in several movies, including Can't Buy Me Love, Sweet Home Alabama, Enchanted, Made of Honor, Valentine's Day and Transformers: Dark of the Moon.

It is unclear if the couple had previously separated before announcing the news of their split.