Agents of SHIELD's Cal will mine the Index to fuel his vendetta against Coulson in "One of Us."

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Skye's father has a teeny tiny rage problem...oh, who are we kidding? The Doctor makes Hulk look like a fluffy puppy and, unfortunately for SHIELD, the Director has attracted his fury. Somewhere in between stealing his daughter's affections and killing Whitehall, Coulson managed to create an enemy.

Not everyone on the Index is particularly thrilled with Fury's old organization. Those who have been locked away or forced to keep a lid on their powers will rally behind Cal, taking down innocents in their quest for revenge (see video below).

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While two of the baddies identities are unknown, it has been confirmed that Drea De Matteo will play the razor sharp Karla Faye Gideon and Jeff Daniel Philips will portray the Bane lookalike, Angar (see photo above).

"Drea is someone on the index. Delightful, and she gets to spend a lot of time with Cal and they have sort of a shared love of SHIELD," executive producer Jeffery Bell told ComicBook.com while Jed Whedon added that de Matteo's character is somewhat "misunderstood...I think she has a heart of gold."

Find out more when Cal and his cohorts launch their attack on March 17.

Agents of SHIELD airs Tuesdays at 9 p.m. ET on ABC.

Tags: Marvel's Agents of S.H.I.E.L.D. television ABC