Whether it's wrestling over the remote, sneak attack wedgies, or debating over who is mom's favorite, the bond of brotherhood is a special connection where even when you don't get along you still have each others back at the end of the day.

In honor of National Brothers' Day, Enstarz has compiled a list of some of the greatest brother teams in film and television.

Sam and Dean Winchester (Supernatural)

The sons of monster hunters, these two CW mainstays have been through (literally) Heaven and Hell together, even when they didn't see eye to eye. Supernatural ran for 15 seasons, giving fans plenty of time to watch Dean and Sam's differing personalities become one of the most believable brother relationships on television.

Dean (Jensen Ackles), with his gruff demeanor, played well against the more intellectual Sam (Jared Padalecki), creating a fun, snarky buddy vibe that got them out of some tough scrapes.

Between the fast-paced monster-of-the-week storylines and classic rock soundtrack, these two deserve a cold one raised in their honor.

Supernatural is streaming now on Netflix and Peacock.

Thor and Loki (Marvel's Thor)

Though not brothers by blood, Thor (Chris Hemsworth) and Loki (Tom Hiddleston) bring one of the more entertaining dynamics to the list. Two of the more seasoned characters in the MCU, we have seen the mighty Thor put up with more than his fair share of Loki's shenanigans - you know, like taking over the Earth with an alien invasion.

Written with all of the jealous ticks of a younger, adopted child, Loki fluctuates between mischievous and softhearted. These constant mood swings not only keep Thor on his toes, having to clean up his brother's messes, but also lead him to better understand the motivations behind Loki's actions, bringing these very different personality types together as family.

All things Thor can be found streaming on Disney+ - and the new one, Thor: Love and Thunder, will be in theaters very soon.

Jake and Elwood Blues (The Blues Brothers)

From the comedic minds of Saturday Night Live legends Dan Aykroyd and John Belushi come the musical comedy duo The Blues Brothers. Draped in black suits and fedoras, the Motown-loving brothers became an instant hit with fans when they first performed on SNL back in 1976.

The characters were eventually spun off into a popular feature film where, after being released from a stay in prison, "Joliet" Jake (Belushi) is reunited with his brother Elwood (Aykroyd) and they go on a "mission from God" to get their old band back together and raise enough money to save the orphanage they were raised in.

Featuring the musical talents of Aretha Franklin, Cab Calloway, and Ray Charles, just to name a few, this comedy quickly became a cult classic with fans.

The Blues Brothers is available on Peacock.

Sonny and Michael Corleone (The Godfather)

In the Francis Ford Coppola classic The Godfather, audiences were taken on a journey through the lives of mafia crime family The Corleones.

This movie touts an all star cast, including Marlon Brando as Don Vito, the head of the family; and his sons, hot-headed ,Sonny played by James Caan, and the put-upon veteran, Michael played by Al Pacino.

These brothers soon become embattled in a power struggle to take over the family business, after Vito is incapacitated by a rival mob. The normally measured Michael is looked upon as the best choice to lead - though he had no intention of ever getting involved with a life of crime. Unsure if his older brother Sonny, who is quick to fly off the handle when pushed, can keep his cool as Don, Michael reluctantly takes the position, leading to an epic narrative about mixing business with family.

The Godfather is available to rent on Amazon Prime.

Jack and Ace Spade (Heels)

Two of the newer brother pairings on this list are the small town wrestlers Jack and Ace Spade from the just renewed Starz series Heels. The show tells the story of Jack Spade (Stephen Amell) who finds himself at odds with his younger brother Ace (Alexander Ludwig) after their wrestler/promoter father kills himself, leaving Jack to keep the family wrestling club afloat.

Jack, the overworked older brother, is constantly trying to make sure Ace's impetuous nature doesn't get the best of him in or outside the ring. What starts as a sibling rivalry, soon evolves into a well crafted family drama, leading Jack to make his once local hero little brother into a heel, straining an already rough relationship. A tightly written drama, Heels goes beyond the mat in terms of gripping storytelling and powerful character building.

Heels is available on Starz.

Brennan Huff and Dale Doback (Step Brothers)

Reuniting one of the funniest on-screen duos of all time, Step Brothers runs the gamut of comedy gold, with its stars Will Ferrell and John C. Reilly. The film revolves around two aimless man-children who are forced to to get alon,g when Brennan's mother marries Dale's father - eventually learning that they have more in common than they could have ever imagined.

What makes this movie so utterly hysterical is the way Ferrell and Reilly play their characters the way children would in real life: spiteful, bratty, and completely immature. Once they begin to learn about each other, what begins as an acerbic comedy quickly becomes a buddy team-up so well-handled they might as well be related.

Over the top and completely ridiculous, very few actors could make two such cartoonish characters work so brilliantly.

Step Brothers is available on Peacock.

Shawn and Marlon Williams (The Wayans Bros.)

The Wayans family has made a business out of comedy for decades. Keenan Ivory, Damon, Kim, Shawn, and Marlon have starred in several films and television shows since the 1980s. Everything from In Living Color, I'm Gonna Git You Sucka, and the Scary Movie franchise has had a Wayans name attached in one way or another. But when Shawn and Marlon decided to play brothers on a sitcom, they really got to showcase how well the family works together on screen.

The Wayans Brothers aired for four seasons on the-then WB Network, telling the story of two brothers who get into wacky situations with their oddball father 'Pops,' played by the late great John Witherspoon.

The series was a hit with fans as it allowed the pair to let loose and take their on-screen versions for a comedic walk. Shawn acted as the straight man, while Marlon would get to display his physical comedy skills. (Being actual brothers really helps when you're trying to make art imitate life.)

Tyrion and Jaime Lanister (Game of Thrones)

The show may not have ended the way it should have, but Game of Thrones was a hell of a ride to get there. Dealing with family drama and social status, two of the stand-out characters who deserve to be on the Best Brothers list would have to be the diminutive intellectual Tyrion (Peter Dinklage) and his sister loving, kingslayer brother Jaime Lanister (Nikolaj Coster-Waldau).

What made this pair so intriguing was the favorite son/black sheep dynamic between them. Tyrion, the womanizing drunk, who was driven to a life of debauchery due to his looked-down-upon small stature. A brilliant tactician with a sharp tongue, he was the best choice to be the future leader of his house.

Conversely, as the perfect son, Jaime was a powerful soldier with a dark secret - being in love with his sister. As at-odds as they were on the show, their opposition came from family obligations, which gave their characters plenty to work through.

Tags: National Brother’s Day supernatural Game of Thrones The Wayans Brothers The Godfather the cw jensen ackles