Ashton Kutcher had a special message for Charlie Sheen when he visited Jimmy Kimmel Live on Wednesday and the latter was quick to respond.

"Dude, shut the f--k up," Kutcher said. "Seriously, like enough already. Like it's like three years later and you're still blowing me up on Twitter. Like come on dude, really?"

The 35-year-old was referring to mean messages Sheen continuously sends Kutcher, the actor who took his job on Two and Half Men three years ago.

For example, in January Sheen tweeted: "Hey Ashton sorry bro all good. now quit barfing on my old brilliant show. Remember Punk'd? how duz it feel?"

Sheen, who was axed from the show in 2011, responded to Kutcher's latest remark via the social network with a threat.

"Ashton message received. so sorry u sounded like me! well done! my bad I was pissed at other crap & took it out on you. hope u r good," he tweeted on Thursday.

"Dood, you ever tell me to shut the F*** up, EVER again, and I'll put you on a hospital food diet for a year."

The 48-year-old actor was fired from the show after he rejected requests from Warner Brothers and CBS to enter rehabilitation. At the time, TMZ published Sheen's response to getting fired and it seemed the actor wasn't bothered.

"I"m thrilled," Sheen told the website. "It insulates me from having to redundantly see myself in the idiotic bowling shirt. Perhaps if Warner Bros. spent as much time and energy focusing on THEIR show, it wouldn't be such a steaming pile of a--."