It's one of the most highly-anticipated upcoming shows for the Fall, and finally, Ryan Murphy is dishing details about Scream Queens.

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The American Horror Story and Glee co-creator is teaming up once again with Brad Falchuk and Ian Brennan on the new show, which has been teased as a horror-comedy about a murderer stalking a college sorority. The project, based on 80s/90s slasher flicks, has an all-star cast attached to it including Emma Roberts, Jamie Lee Curtis, Lea Michele, Keke Palmer, Oliver Hudson, Abigail Breslin, Nick Jonas and Ariana Grande.

Murphy has kept quiet about the project thus far, but opened up to Entertainment Weekly about the show in an April 23 interview--revealing that the all-star cast would find themselves being picked off one by one as the show continued through its episodes.

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"One thing we've said to the cast is that every episode someone is going," he said. "Its always somebody you least suspect or expect. The killer is on a reign of terror...There's a real tune-in factor because it's like, 'Who's going to be picked off this week? And also who is the killer?' Every episode, you get clues as to who the killer is going to be and then all of these clues accumulate."

However, he cautions that unlike Horror Story, which completely reboots with each new season, some of the characters from the new show will make it through to the end--and will be a part of the next season to air--though he won't reveal who will or won't die just yet.

"It's different than Horror Story. Jamie Lee and I were talking about that in horror movies, particularly in that era, there was always the last girl, the final girl," Murphy said. "So we're playing with that. Whoever survives--and there will be people who will survive--they will go on next season to a new location and a new terror.Unlike Horror Story, which completely reboots, this has some of the continuity in that some of the characters and some of the relationships continue into a new world."

Scream Queens premieres this fall on FOX.