Life is fleeting, and that is an adage Quantico will bring into heartbreakingly sharp relief during the midseason premiere.

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Simon Asher (Tate Ellington) and Alex Parrish (Priyanka Chopra) unwittingly turned the FBI's emergency headquarters into so much smoke and rubble during "Inside," and their mistake will result in major casualties. Showrunner Josh Safran delivered the devastating statistics while speaking with TV Line.

"I can tell you that 32 people are not going to make it out of that building alive," Safran said.

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Oh, Simon, what have you done?

The casualties won't just gut the Bureau's big brass, either. Of the NATs, Caleb (Graham Rogers) and Shelby's (Johanna Braddy) lives are on the line, and those are only the ones we know of. If the youngsters bite the dust, the future timeline will loose some fan favorites.

As those 32 characters march of screen, Quantico will bring in a host of fresh faces. Don't worry - these characters won't mysterious emerge from the background of Alex's NAT class. Instead, TV Line reports that they will belong to the year above our budding agents.

Find out more when Quantico returns to ABC on March 6 at 10 p.m. ET.