After Wednesday night's shocking blindside, it is now anyone's game on CBS's Survivor: San Juan del Sur with the two biggest power players out one after the other.

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Though Survivor had been setting up the huge conflict between Josh Canfield and Jeremy Collins for several episodes, viewers were shocked to see Jeremy voted just three days after Josh on Wednesday night's episode.

Power couple Jon Misch and Jaclyn Schultz completely took control of the game by manipulating Missy Payne and Baylor Wilson into voting out Jeremy out of paranoia about Immunity Idols. Reed Kelly, a free agent, joined them and successfully made a huge power move.

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Now, with alliances broken and randomly forming, it truly is anyone's game at this point. Many had been assuming either Josh or Jeremy would win this season of Survivor, but with both of them out it could be pretty much anyone.

Survivor host Jeff Probst previewed the next episode in his new interview with Entertainment Weekly, and also teased the intense Immunity Challenge to come.

"Yes alliances are definitely 'up for grabs' and the immunity challenge demonstrates how incredibly demanding this game is on the mind, body, and soul," Probst said.

It is not clear if Reed will stick with the two couples, Jon and Jaclyn and Missy and Baylor, or if he will switch back and vote with Alec Christy, Keith Nale and Wes Nale. Meanwhile, Natalie Anderson is now without her closest ally, Jeremy, so she is a free agent.

If Natalie and Reed both switch over to Alec, Keith and Wes, they could form a new majority and take out Jon and Jaclyn and Missy and Baylor. It remains to be seen if those two couples made the right decision in voting out their ally so soon.

Survivor: San Juan del Sur airs Wednesdays at 8 p.m. ET/PT on CBS.