Enstars' Grammy Flashbacks: The Show-Stopping Performances of the 2000s

In part two of our series, Enstars continues to look at some of the most memorable Grammy moments of the past decade.

Whitney Houston: "It's Not Right, But It's Okay"/ "I Learned From The Best" (2000)

Sadly, this medley marked the last time Whitney Houston performed on the Grammys stage. Houston performed two of her hits from her Grammy-nominated album My Love is Your Love. While Houston took the Staples Center audience to the club with "It's Not Right, But It's Okay," she gave the audience chills when she sang the Diane Warren ballad "I Learned From The Best."

Moments after the performance, Houston earned her final Grammy award for Best R&B Female Performance for "It's Not Right, But It's Okay."

Santana And Rob Thomas: "Smooth" (2000)

2000 was a memorable year for Carlos Santana. He tied Michael Jackson's record of winning the most Grammy Awards in one night! Santana celebrated his victory by reuniting with Matchbox Twenty frontman Rob Thomas as they brought Latin rock into the Staples Center with an impeccable performance of "Smooth."

Eminem And Elton John: "Stan" (2001)

Before Eminem was headlining both Bonnaroo and Coachella, Detroit's rap king was making headlines for his controversial lyrics. When the Recording Academy announced that Eminem would be making his Grammy debut by performing "Stan" alongside music legend Elton John, the Gay and Lesbian Alliance Against Defamation threatened to boycott the program.

The duo proved GLAAD wrong and delivered one of the most memorable Grammy moments of the 2000s.

Simon And Garfunkel: "The Sound Of Silence" (2003)

When The Grammy Awards returned to New York City in 2003, it marked the first time that the music awards show was held since 9/11. One of the show's most significant performances of the evening belonged to estranged music duo Paul Simon and Art Garfunkel. The men performed "The Sound of Silence."

By using one guitar and their haunting vocals, Simon and Garfunkel delivered a moving performance that mesmerized the Madison Square Garden audience.

Prince And Beyoncé: Medley (2004)

Prince and Beyoncé Knowles-Carter brought the audience to their feet when they opened the 2004 Grammy Awards. The duo performed three of Prince's biggest hits: "Purple Rain," "Baby I'm A Star," and "Let's Go Crazy" along with Knowles-Carter's "Crazy in Love."

The duo set the bar incredibly high for future Grammy Award collaborations. 12 years after this epic performance, the world mourned Prince, who tragically passed away on April 21, 2016.

Melissa Etheridge & Joss Stone: "Piece of My Heart" (2005)

The 2005 Grammy Awards marked a homecoming for Melissa Etheridge. The rock singer just finished chemotherapy when the Recording Academy asked her to perform in a tribute celebrating one of her heroes, Janis Joplin.

After Joss Stone warmed up the crowd with opened the segment with "Cry Baby," Etheridge made her glorious comeback with an outstanding cover of "Piece of My Heart" that became a rallying cry for breast cancer survivors everywhere.

Christina Aguilera: "It's A Man's Man's World" (2007)

Four years before she became one of the founding coaches of the NBC singing competition, The Voice, Christina Aguilera delivered a powerful homage to one of her heroes, the Godfather of Soul.

Aguilera's compelling interpretation of James Brown's signature song brought the Staples Center audience to its feet. Ten years later, Aguilera delivered another tribute performance to another one of her heroes, Whitney Houston, at the American Music Awards.

Mary J. Blige: "Be Without You" (2007)

The Queen of Hip-Hop Soul, Mary J. Blige, delivered a legendary performance when she performed at the 2007 Grammy Awards. Backed by an orchestra, Blige delivered one of her best vocal performances of her career when she sang "Be Without You."

11 years after delivering a memorable performance, Blige received a star on the Hollywood Walk of Fame for her contributions to the music world.

Beyoncé & Tina Turner: "Proud Mary" (2008)

For the Grammys' 50th anniversary, the Recording Academy gave Knowles-Carter made one of her lifelong wishes come true as she performed with her idol -- the legendary Tina Turner. After Knowles-Carter introduced her, Turner sang "What's Love Got to Do With It" before the superstars teamed up for "Proud Mary."

This year marks a big year for the music superstars as Knowles-Carter will headline Coachella, while Turner will receive her Lifetime Achievement Award from the Recording Academy and release an autobiography.

The Late Late Show host James Corden will host the 60th Annual Grammy Awards at New York City's Madison Square Garden on Sunday, Jan. 28.

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